Calcium d-Glucarate

Calcium d-glucarate can help prevent certain types of cancer and help lower cholesterol. It's the calcium salt of d-glucarate, a natural substance found in fruits and vegetables such as apples, grapefruits, broccoli and alfalfa sprouts.

Glucuronidation is a chemical process that binds glucuronic acid to various toxins, including carcinogens. Afterwards, the bound complex can be easily removed from the body. This process is blocked by an enzyme called glucuronidase, which is, in turn, blocked by d-glucarate. Normally, d-glucarate does this for an hour or so. Making it into a Calcium salt extends its action to 5 hours. This means the supplement helps the body remove carcinogens easier, faster and longer.

Some of the anti-cancer, detoxification properties of fresh fruits and vegetables may come from their d-glucarate content.

In one experiment, rats given anthracene (a carcinogen) normally develop breast cancer quite quickly. When pretreated with Calcium d-glucarate the tumor development was blocked entirely in 70% of the animals. Subsequent experiments showed that it could also decrease the proliferation of tumors once they were established.

Other experiments established that d-glucarate was effective against a wide variety of carcinogens and tumors such as breast, prostate, lung and colon cancers.

Calcium d-glucarate may be a good supplement to include in your overall health program if you're exposed to carcinogens or if you have a family history of cancer.

In addition, animal experiments showed that Calcium d-glucarate lowered total cholesterol by 13 to 15% and LDL by 30 to 35%.


No side effects have been noted and it is regarded as having little or no toxicity.


500mg 3 times daily.


I recommend Now Foods 500mg capsules.